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More case reports are needed for further understanding of this rare malignant odontogenictumour.
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Background: Ameloblastoma is a locally aggressive odontogenictumour of the mandible and maxilla that, if neglected, can cause severe facial disfigurement and functional impairment.
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Clinical significance: The study helps in assessing the occurrence of the odontogenictumor.
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Myxoma of the jaw is classified as an odontogenictumor although final proof for an odontogenic origin is lacking.
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Histologically, the tumor was composed of clear-cell areas and exhibited a squamous pattern with little nuclear pleomorphism similar to benign squamous odontogenictumor.
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Ameloblastoma is a benign odontogenictumor with an aggressive biological behavior, and the surgical treatment frequently results in failure for the postoperative recurrence.
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This would be expected since the histogenesis of odontogenictumors commonly comes from epithelium that recently performed a secretory activity in tooth formation.
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This would be expected since the histogenesis of odontogenictumors commonly comes from epithelium that recently performed a secretory activity in tooth formation.
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Aims: The aim of this study is to assess the biological role of MMP20 and KLK4 in odontogenictumors.